Posting Number: 000210 Position Type: Scientific Classification: Ongoing Status: Full-Time Department: Genes & Human Disease - Lessard
Job Summary/Basic Function: The Lessard laboratory is seeking a highly motivated, self-starter, Post-doctoral Fellow with the ability to work with optimal resources and little direct supervision to address important questions in the genetics and genomics of the autoimmune diseases Sjögren's syndrome, systemic lupus erythematosus, and neuromyelitis optica. Successful candidates will be proficient in the analysis of genetic data, high-throughput sequencing data and the use of bioinformatics software and databases. The lab is currently interested in bulk and single cell RNA-seq, long non-coding RNAs, ChIP-Seq, ATAC-seq, whole genome sequencing, spatial transcriptomics, scRNA-seq, and SNP-phenotype associations. The lab also has uses molecular approaches to further understand function of genomic features that will work closely with the analyist. Software used in the lab include but not limited to the following: python, UNIX/LINIX, R (and various genomics packages), GATK, HISAT2, PLINK, and MATRIXeqtl. OMRF is an independent, not-for-profit biomedical research institute adjacent to the University of Oklahoma Health Sciences Center (OUHSC) campus in Oklahoma City. Oklahoma City offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy. OMRF's excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic. lab
Minimum Qualifications: Ph.D., M.D., or Ph.D./M.D. Previous experience in biostatistics and/or human genetics/genomics is required. Must have at least one first author publication. Good written skills necessary. Ability to communicate and write summaries of results required.
Minimum Degree Required: Doctorate
Preferred Qualifications: Ideally would have at least two publications with one or more first author, peer-reviewed, English manuscripts in human genetics or genomics. Previous experience with analytical methodologies described above would be ideal.
Physical Demands: Regularly required to stand, use manual dexterity, talk or hear; Frequently required to walk and reach with hands and arms; occasionally sit; frequently lift and/or move up to 50 pounds; vision abilities include close vision, color vision, depth perception and ability to adjust focus. Potential exposure to fumes, airborne particles, or rodent dander. May work with toxic, caustic chemicals, radioactive materials, liquid nitrogen, human tissue or blood. Potential risk of electrical shock. Occasional exposure to cold 4C, and/or extreme cold -80C from freezers. Noise level is usually moderate.