The Department of Translational Genome Sciences in Translational Biology (Research & Early Development) is responsible for applying human genetic & genomic discoveries to support Biogen’s drug discovery research teams and clinical development programs.
We seek to discover transformative medicines for patients with neurodegenerative disease by leveraging new understanding of human disease biology, genetics, and cutting-edge technologies allowing deeper analysis of pathogenic mechanisms. Pushing back the frontier of neurological disease therapeutics lies at the center of Biogen’s mission.
We are looking for a highly collaborative human genetics expert with experience working with epidemiological and clinical data sets and/or clinical trial teams. In this role, the genomic biomarker scientist will work in partnership with therapeutic area research scientists, clinical teams, and Translational Biology colleagues to develop and implement Clinical Trial Genomics Workplans to support R&D disease areas and program priorities.
• Post-graduate experience in human genetics & genomics, diagnostics, or analysis of large data sets
• Ability to translate complex statistical/informatics terminology in such a way that scientifically trained individuals can readily understand their significance 225 Binney Street, Cambridge, MA 02142 • Phone 781 -464-2000 • www.biogen.com
• Ability to work collaboratively with research project teams and/or clinical development program teams is required
• Track record of innovative and impactful research in genetics of complex traits
• Outstanding communication & presentation skills
• Experience with multiple genetics platforms (GWAS, WES & WGS, Sanger, etc.) as well as other genomic profiling technologies (microarrays, RNA-Seq, etc.)
• Post-graduate experience in human genetics and genomics, diagnostics, or analysis of large data sets
• Demonstrated knowledge of pre-clinical and clinical drug development process
• Ph.D. or M.D. in molecular, functional, or clinical genetics
• Partnering with Research & Clinical Development teams, as programs progress from research to development, to identify key questions and priorities that genetics & genomic technologies can address with respect to patient selection, stratification & drug response;
• Providing quantitative and molecular genetics expertise to develop the Clinical Trial Genomics Workplan & help clinical teams optimize their trial strategy and achieve program milestones;
• Accountability for documenting and working cross-functionally to implement the Clinical Trial Genomics Plan;
• Identifying opportunities for external collaborations that supplement internal TGS and TB resources & ensure clinical genetic and genomic biomarker research is at the cutting edge;
• Surveying the literature & attending scientific conferences for discoveries & findings from the genetics community, and integrating findings into opportunities internally; and
• Communicating updates, study findings and analyses with clinical teams, leadership, and collaborators
About Biogen, Inc.
Biogen seeks to discover transformative medicines for patients with Multiple Sclerosis (MS) by leveraging new understanding of human disease biology, genetics, and cutting-edge technologies allowing deeper analysis of pathogenic mechanisms. Pushing back the frontier of neurological disease therapeutics lies at the center of Biogen’s mission.